This foundational course introduces the principles, history, and multidisciplinary scope of producing biological materials and systems beyond Earth. Participants explore how the extreme environment of space, including microgravity, radiation, and isolation, creates unique opportunities for cellular processes, microbial behavior, and biofabrication technologies. The curriculum examines bioreactor design, tissue engineering, and biomaterial production, alongside the resource utilization and automation factors critical for establishing commercially viable manufacturing capabilities.

Drawing on real mission data, biomanufacturing experiments, and ongoing research aboard the International Space Station, participants develop a comprehensive understanding of the biological and engineering foundations enabling space-based production. The course lays the groundwork for identifying business opportunities beyond low Earth orbit, equipping industry professionals with the strategic insight needed to develop self-sufficient production systems on the Moon, Mars, and beyond.